Preparation of new techniques for cardiac glycosides
The flora of the earth is an inexhaustible resource of great remedies. There are over 12,000 species of medicinal plants and have been used to treat various diseases for thousands of years. However, only infused with herbs is not sufficient to achieve a positive healing drugs should be obtained from vegetable raw materials and knowledge in the mechanism of action. For example, to prepare a great cardiovascular activity digoxin effective methods must be developed to extract medicinal substances glycosides.This problem was successfully solved by researchers from the National Research Institute of Organic Chemistry and Technology, under the direction of Project Manager Galina Mikhailovna Komissarov and All Russian Institute of Medicinal and Aromatic Plants, under the leadership of
member corresponding Dyumaev Kirill Mikhailovich. The International Centre for Science and Technology supports scientific research.For 200 years, the use of cardiac glycosides in medical practice views on the mechanism of their action and how to have received the drugs from the series of cardiac glycosides has changed considerably. But one thing remains the same application of cardiac glycosides in heart failure can really early or latent functional heart rhythm disturbances and prevent the development of overt heart failure. A number of patented processes for the production of digoxin from Digitalis lanata, with the use of natural enzymes currently available.However, this patented process, a number of important shortcomings. The most important of them, says Galina
Mikhailovna Komissarova is low stability of the fermentation due to the quality of raw materials herbal. Second, toxic solvents and explosives, which are expensive materials used in these methods. In addition, many have to be carried out in stages of purification technology for the final drug, this is a very complicated process.During the project manager of the State Scientific Center of the State Research Institute of
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