Amazing Brain Neuroscientist documents dialogue during sleep
In a paper published in the Proceedings of the National Academy of Sciences, a research group led by a Brown University neuroscientist describes records of innovative activity in two brain regions during deep sleep. The dishes were caught between the hippocampus and the neocortex, the brain areas where scientists believe that memories are made and stored. The results were surprising. The researchers found that electrical activity in brain cells of sleeping mice was not completely random, the performance of previous research.Instead, the team found that the slow and regular firing of excitatory cells was in the neocortex, a fraction of a second repeat at the hippocampus. The echo of cortical activity was in the three parts of the hippocampus. Excitatory cells in the dentate gyrus
showed a strong echo, while CA3 region cells showed a weak echo. The cells in the CA1 region responded in the opposite direction, to calm down when the cortex was active.Surprisingly enough, Brown said Mayank Mehta, assistant professor of neuroscience who led the study. Weve been a century that the hippocampus and the neocortex are anatomically connected known. But this is the first time we have seen the effect of this compound in the brain of live animals. The dialogue is quite unexpected and complex, suggesting that this simple circuit of the brain much more complex than we introduced. To perform the experiments, the researchers recorded electrical activity in the mouse brain.To mimic the deepest sleep state, when neuroscientists believe that memory storage occurs,
animals were anesthetized and electrodes. One electrode measured cellular activity in the cerebral cortex. Other measures of activity in the cells of the three regions of the hippocampus.Bert Sakmann, the physiologist and Nobel laureate, co-author, created the recording technique of the novel in the Max-Planck-Institute for Medical Research in Germany. Thomas Hahn, a graduate student in the Department of Physiology
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